NAD+

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in all living cells, playing a central role in energy metabolism and vital cellular functions. By facilitating the conversion of nutrients into adenosine triphosphate (ATP)—the primary energy currency of the cell—it is essential for maintaining efficient mitochondrial function. As organisms age, natural levels of NAD+ decline, which is often associated with a decrease in metabolic efficiency and the onset of various age-related cellular processes.

Beyond its role in energy production, NAD+ serves as a vital substrate for enzymes like sirtuins, which are involved in regulating cellular health, DNA repair, and gene expression. Because of its fundamental importance in supporting mitochondrial integrity and overall cellular resilience, research into NAD+ supplementation and its potential to influence biological aging and metabolic health has become a significant area of focus in modern biochemistry and longevity science.